An allergen is a type of antigen that produces an abnormally vigorous immune response in which the immune system fights off a perceived threat that would otherwise be harmless to the body. In technical terms, an allergen is an antigen capable of stimulating a type-I hypersensitivity reaction in atopic individuals through Immunoglobulin E (IgE) responses.[1] Most humans mount significant Immunoglobulin E responses only as a defense against parasitic infections. However, some individuals may respond to many common environmental antigens. This hereditary predisposition is called atopy. In atopic individuals, non-parasitic antigens stimulate inappropriate IgE production, leading to type I hypersensitivity. Sensitivities vary widely from one person (or other animal) to another. A very broad range of substances can be allergens to sensitive individuals.

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You can find here features and tools about allergenicity

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Classification of allergens

Allergy Pathways
Allergy Pathways

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Sequence search based on Codex regulations

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You can find here most important papers about allergens and allergenicity

IrAller Statistics

Date of Establishment: 2014-01-01
Last update: 2014-01-01
Taxonomic-protein groups:
Allergens total (Peer Reviewed):
Allergens families:
Version: 1

The IrAller team

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    Project leader and database design:
    Najaf Allahyari Fard
    Zarrin Minuchehr

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    Scientific advisory board:
    Mehdi Sadeghi
    Zarrin Minuchehr
    Ghasem Ahangari
    Amir Mousavi
    Masoud Rahgozar
    Najaf Allahyari Fard

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    Site administration:
    Seyed Kazem Hosseini

IR Aller
National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran

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